Raife Gülru Gezer was born in Istanbul in 1979. She graduated from the Department of Political Science and International Relations of the Boğaziçi University in the year 2000. She completed her MA in European Political and Administrative Studies at the College of Europe in Brugge, Belgium in 2010.

Raife Gülru Gezer started her career in 2000 as assistant editor at the international news department of the NTV news channel. In 2003 she joined the Ministry of Foreign Affairs of Turkey and began working at the European Union Political Affairs Deputy Directorate as a Career Diplomat. In 2007 she was posted to the Turkish Embassy in Damascus where she worked for two years as Second Secretary. Later on she was sent to the Turkish Permanent Representation to the EU in 2009. Returning to Ankara in 2010 she was appointed as the Chief of Cabinet of the Under Secretary of the Ministry of Foreign Affairs. After serving for four years in Ankara, she was appointed as the Consul General of Turkey to Los Angeles. In 2017 she was transferred to the Turkish Embassy in Moscow where she served as Senior Counsellor. Returning to Ankara in 2019 and working at the Diplomatic Academy as Head of Department for 6 months, she was appointed as Chief of Cabinet of the Deputy Minister.

Gülru Gezer joined TEPAV in September 2022 as a Foreign Policy Program Director.